Alzheimer’s Disease Assessment Scale (ADAS)

Rosen and Mohs‚ 1983

Cognitive Behavior

1. Spoken language ability (0–5)

2. Comprehension of spoken language (0–5)

3. Recall of test instructions (0–5)

4. Word-finding difficulty (0–5)

5. Following commands (0–5)

6. Naming objects and fingers (0–5)

7. Constructions—copying forms (0–5)

8. Ideational praxis (0–5)

9. Orientation to time‚ place‚ and person (0–8)

10.Word recall memory test (0–10)

11.Word recognition memory test (0–12)

Noncognitive behavior

12.12. Tearful appearance (0–5)

13.13. Appears or reports depressed mood (0–5)

14.14. Concentration‚ distractibility (0–5)

15.15. Lack of cooperation in testing (0–5)

16.16. Delusions (0–5)

17.17. Hallucinations (0–5)

18.18. Pacing (0–5)

19.19. Increased motor activity (0–5)

20.20. Tremors (0–5)

21.21. Increased or decreased appetite (0–5)

For each severity scale‚ 0 signifies no impairment on a task or the absence of a particular behavior. A rating of 5reflects severe impairment or high frequency of abehavior

This instrument can be found at: www.a4ebm.org/sites/default/files/Measuring%20Health.pdf

Rosen‚ W.G‚ Mohs‚ R.C & Davis‚ K.L. (1984). A new rating scale for Alzheimer’s disease. American Journal of Psychiatry‚ 141(11): 1356-1364.

Mohs‚ R.C & Cohen L (1988). Alzheimer’s Disease Assessment Scale (ADAS). sychopharmacology Bulletin‚ 24: 627-628.

Mohs‚ R.C.‚ Rosen‚ W.G.‚ Greenwald‚ B.S‚ et al. Neuropathologically validated scales for Alzheimer’s disease. In: Crook T‚ Ferris S‚ Bartus R‚ eds. Assessment in geriatric psychopharmacology. New Canaan‚ Connecticut: Mark Powley‚ 1983:37–45.

Rosen‚ W.G.‚ Mohs‚ R.C.‚ Davis‚ K.L. Longitudinal changes: cognitive‚ behavioral‚ and affective patterns in Alzheimer’s disease. In: Poon LW‚ Crook T‚ Davis KL‚ et al.‚ eds. Handbook for clinical memory assessment of older adults. Washington‚ DC: American Psychological Association‚ 1986:294–301.

Talwalker‚ S.‚ Overall‚ J. E.‚ Srirama‚ M. K.‚ & Gracon‚ S. I. (January 01‚ 1996). Cardinal features of cognitive dysfunction in Alzheimer’s disease: a factor-analytic study of the Alzheimer’s Disease Assessment Scale. Journal of Geriatric Psychiatry and Neurology‚ 9‚ 1‚ 39-46.

Mohs‚ Rich‎ard C.; Knopman‚ David; Petersen‚ Ronald C.; Ferris‚ Steven H.; Ernesto‚ Chris; Grundman‚ Michael; Sano‚ Mary; Bieliauskas‚ Linas; Geldmacher‚ David; Clark‚ Chris; Thai‚ Leon J. (1997). Development of Cognitive Instruments for Use in Clinical Trials of Antidementia Drugs: Additions to the Alzheimer’s Disease Assessment Scale That Broaden Its Scope. The Alzheimer’s Disease Cooperative Study. Alzheimer Disease & Associative Disorders. 1997;11(Suppl 2):S13–21

Weyer‚ G.‚ Erzigkeit‚ H.‚ Kanowski‚ S‚ et al. (1997). Alzheimer’s Disease Assessment Scale: reliability and validity in a multicenter clinical trial. Int Psychogeriatr‚ 9:123–138.

McDowell‚ Ian. (2006). Measuring Health: A Guide to Rating Scales and Questionnaires‚ Third Edition. OXFORD UNIVERSITY PRESS

Skinner‚ Jeannine.‚ Carvalho‚ Janessa O.‚ Potter‚ Guy G.‚ et al. (2012). The Alzheimer’s Disease Assessment Scale-Cognitive-Plus (ADAS-Cog-Plus): an expansion of the ADAS-Cog to improve responsiveness in MCI. Brain Imaging Behav‚ 6(4):489-501.

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